Monday, 4 June 2018

A Recent History of HNO (Nitroxyl) Chemistry, Pharmacology and Therapeutic Potential.

Abstract

Due to the excitement surrounding the discovery of nitric oxide (NO) as an endogenously generated signaling molecule, numerous other nitrogen oxides were also investigated as possible physiological mediators. Among these was nitroxyl (HNO). Over the past 25 years or so, a significant amount of work by this lab and many others has discovered that 

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